Renal dysfunction after myocardial revascularization: Risk factors, adverse outcomes, and hospital resource utilization

Abstract

Background: Acute changes in renal function after elective coronary bypass surgery are incompletely characterized and represent a challenging clinical problem. Objective: To determine the incidence and characteristics of postoperative renal dysfunction and failure, perioperative predictors of dysfunction, and the effect of renal dysfunction and failure on in-hospital resource utilization and patient disposition after discharge. Design: Prospective, observational, multicenter study. Setting: 24 university hospitals. Patients: 2222 patients having myocardial revascularization with or without concurrent valvular surgery. Measurements: Prospective histories, physical examinations, and electrocardiographic and laboratory studies. The main outcome measure was renal dysfunction (defined as a postoperative serum creatinine level