Selective targeting of fluorescent nanoparticles to proteins inside live cells

  • Liße D
  • Wilkens V
  • You C
 et al. 
  • 43

    Readers

    Mendeley users who have this article in their library.
  • 0

    Citations

    Citations of this article.

Abstract

Tracking single proteins in cells: An optimized substrate based on a click reaction was designed for specific, irreversible targeting of nanoparticles to proteins fused to an engineered haloalkane dehalogenase (HaloTag) in the cytoplasm of life cells. Thus, proteins in the membrane of mitochondria could be tracked over extended times and with nanometer resolution (see picture).

Author-supplied keywords

  • click chemistry
  • fluorescence spectroscopy
  • nanoparticles
  • proteins

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free