Objective: To examine the long-term relationship between sleep duration and type 2 diabetes or impaired glucose tolerance (IGT). Methods: Body composition measurements and self-reported sleep duration were determined in a longitudinal sample of 276 individuals aged 21 to 64 years followed for a mean of 6 years. Risk factors of type 2 diabetes/IGT over the follow-up were determined and relative risks (RRs) calculated for the development of type 2 diabetes/IGT by sleep duration group. Results: Independent risk factors of type 2 diabetes/IGT over the follow-up included age, obesity, sleep duration, and glucose/insulin homeostasis indicators. Using adults with 7-8 h of sleep as a reference, the adjusted RR for the development of type 2 diabetes/IGT was 2.78 (1.61-4.12) for those with ≤6 h of sleep and 2.54 (1.42-3.53) for those with ≥9 h of sleep. These elevated RRs remained significant after adjustment for body mass index, waist circumference or percent body fat. Conclusion: Short and long sleeping times are associated with a higher risk of developing type 2 diabetes/IGT, independent of several covariates. These results suggest that sleep duration may represent a novel risk factor for type 2 diabetes/IGT. © 2009 Elsevier B.V. All rights reserved.
CITATION STYLE
Chaput, J. P., Després, J. P., Bouchard, C., Astrup, A., & Tremblay, A. (2009). Sleep duration as a risk factor for the development of type 2 diabetes or impaired glucose tolerance: Analyses of the Quebec Family Study. Sleep Medicine, 10(8), 919–924. https://doi.org/10.1016/j.sleep.2008.09.016
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