A series of new N-[(3-ferrocenyl-1-phenylpyrazol-4-yl)methyl] α-amino acids were prepared and characterized by a range of spectroscopic techniques and cyclic voltammetry. The in vitro antitumor activity of all synthesized compounds was investigated against cervix adenocarcinoma HeLa, melanoma Fem-x and myelogenous leukemia K562 cell lines using the MTT method. Tryptophan derivative 1l exhibited the highest cytotoxic activity in the cell growth inhibition of all three types of cell lines. © 2009 Elsevier B.V. All rights reserved.
CITATION STYLE
Joksović, M. D., Marković, V., Juranić, Z. D., Stanojković, T., Jovanović, L. S., Damljanović, I. S., … Vukićević, R. D. (2009). Synthesis, characterization and antitumor activity of novel N-substituted α-amino acids containing ferrocenyl pyrazole-moiety. Journal of Organometallic Chemistry, 694(24), 3935–3942. https://doi.org/10.1016/j.jorganchem.2009.08.013
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