Tau aggregates and tau pathology

  • Hernández F
  • Avila J
  • 19


    Mendeley users who have this article in their library.
  • 27


    Citations of this article.


There is controversy in some neurodegenerative disorders whether the presence of aberrant aggregates in a neuron could have a toxic or a protective effect. In some disorders like in encephalopathies (prion disease), protein aggregates are toxic for the neuron. In other disorders, like Huntington disease, a protective role has been suggested for the aggregates of huntingtin. In this paper, we review the role of tau aggregation and hypothesize that tau aggregates could have an insufficient protective role in damaged neurons.

Author-supplied keywords

  • GSK3
  • Tau aggregation
  • Tau phosphorylation
  • Tauopathology

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Félix Hernández

  • Jesús Avila

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free