The control of telomerase activity at chromosome ends by telomere-binding proteins is critical for telomere length homeostasis. Two recent papers identify TPP1 as a critical mediator of this control. TPP1 forms part of the telomeric shelterin complex while also associating with telomerase, stimulating its activity and processivity. © 2007 by American Chemical Society.
CITATION STYLE
Cristofari, G., Sikora, K., & Lingner, J. (2007). Telomerase unplugged. ACS Chemical Biology, 2(3), 155–158. https://doi.org/10.1021/cb700037c
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