Towards a multidisciplinary and integrated strategy in the assessment of adverse health effects related to air pollution: the case study of Cracow (Poland) and asthma

  • Oudinet J
  • Meline J
  • Chelmicki W
 et al. 
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Complex interaction between anthropogenic activities, air quality and human health in urban areas, such as in Cracow sustains the need for the development of an interdisciplinary and integrated risk-assessment methodology. In such purpose, we propose a pilot study performed on asthmatics and based on a combined use of a biomarker, such as metallothionein 2A (MT-2A) in the characterization of human exposure to one or a mixture of pollutants and of Geographical Information Systems (G.I.S.) which integrates climatic and urban anthropogenic parameters in the assessment of spatio-temporal dispersion of air pollutants. Considering global incidence of air pollution on asthma and on peripheral blood lymphocytes MT-2A expression should provide a complementary information on biological risks linked to urban anthropogenic activities. Such study would help for the establishment of a sustainable development in urban areas that can maintain the integrity of air quality and preserve human health.

Author-supplied keywords

  • *Urban Health
  • Air Movements
  • Air Pollution/*adverse effects/analysis
  • Asthma/*etiology/immunology
  • Biological Markers/blood
  • Cities
  • Environmental Exposure
  • Environmental Monitoring/*methods
  • Geographic Information Systems
  • Humans
  • Metallothionein/blood
  • Poland
  • Risk Assessment/methods

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  • J P Oudinet

  • J Meline

  • W Chelmicki

  • M Sanak

  • D W Magdalena

  • J P Besancenot

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