Urinary isoflavone excretion as a compliance measure in a soy intervention among young girls: A pilot study

  • Maskarinec G
  • Oshiro C
  • Morimoto Y
 et al. 
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Objective: To investigate the compliance of young girls with a soy intervention. Design: An 8-week dietary intervention and urine sample collection. Setting: Free-living girls. Subjects: A convenience sample of 8- to 14-y-old girls (20 started and 17 finished the study) recruited through flyers distributed to staff members and previous study participants. Intervention: The girls consumed one daily serving of soymilk, soy nuts, or tofu, completed 3-day food records, kept daily soy intake logs, and collected weekly urine samples. Main outcome measures: Compliance with the intervention was evaluated by daily soy intake logs, 3-day food records analyzed by the center's Food Composition and Food Groups Servings Databases, and weekly urinary isoflavone excretion using high-pressure liquid chromatography. The statistical analysis included paired t-tests, analysis of variance, and Spearman's rank-order correlation coefficients. Results: Daily soy intake logs indicated a mean intake of 6.28 servings out of a maximum of 7.0 servings per week. The food records revealed a six-fold increase in isoflavone intake during the study period (P

Author-supplied keywords

  • Compliance
  • Girls
  • Intervention
  • Nutrition
  • Phytoestrogens
  • Soy foods

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  • Gertraud Maskarinec

  • C. Oshiro

  • Y. Morimoto

  • S. Hebshi

  • R. Novotny

  • A. A. Franke

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