OBJECTIVE: To determine the extent of variability in testing and treatment of children with bronchiolitis requiring intensive care. METHODS: This prospective, multicenter observational study included 16 academic children's hospitals across the United States during the 2007 to 2010 fall and winter seasons. The study included children<2 years old hospitalized with bronchiolitis who required admission to the ICU and/or continuous positive airway pressure (CPAP) within 24 hours of admission. Among the 2207 enrolled patients with bronchiolitis, 342 children met inclusion criteria. Clinical data and nasopharyngeal aspirates were collected. RESULTS: Respiratory distress severity scores and intraclass correlation coefficients were calculated. The study patients' median age was 2.6 months, and 59% were male. Across the 16 sites, the median respiratory distress severity score was 5.1 (interquartile range: 4.5-5.4; P
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Pierce, H. C., Mansbach, J. M., Fisher, E. S., Macias, C. G., Pate, B. M., Piedra, P. A., … Camargo, C. A. (2015). Variability of intensive care management for children with bronchiolitis. Hospital Pediatrics, 5(4), 175–184. https://doi.org/10.1542/hpeds.2014-0125
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