Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes

  • F.G. H
  • S. W
  • G.G. Z
 et al. 
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Abstract

Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD). © 2010 by the authors.

Author-supplied keywords

  • *C reactive protein/ec [Endogenous Compound]
  • *Cuban American
  • *body mass
  • *non insulin dependent diabetes mellitus/ep [Epide
  • *non insulin dependent diabetes mellitus/et [Etiol
  • *race
  • *waist circumference
  • adult
  • antidepressant agent
  • antidiabetic agent
  • antihypertensive agent
  • antilipemic agent
  • article
  • body fat
  • cardiovascular disease/ep [Epidemiology]
  • cardiovascular disease/et [Etiology]
  • cardiovascular risk
  • controlled study
  • female
  • human
  • major clinical study
  • male
  • nonsteroid antiinflammatory agent
  • obesity/pc [Prevention]
  • population based case control study
  • protein blood level
  • protein determination
  • sex difference

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Authors

  • Huffman F.G.

  • Whisner S.

  • Zarini G.G.

  • Nath S.

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