Warfarin-antibiotic interactions in older adults of an outpatient anticoagulation clinic

  • Ghaswalla P
  • Harpe S
  • Tassone D
 et al. 
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Abstract

Background: Several classes of drugs, such as antibiotics, may interact with warfarin to cause an increase in wafarins anticoagulant activity and the clinical relevance of warfarin-antibiotic interactions in older adults is not clear. Objective: The aim of this study was to determine the effect of oral antibiotics, such as amoxicillin, azithromycin, cephalexin, ciprofloxacin, levofloxacin, and moxifloxacin, on the international normalized ratio (INR) in patients

Author-supplied keywords

  • antibiotics
  • drug interactions
  • older adults
  • warfarin

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Authors

  • Spencer HarpeMidwestern University - Chicago College of Pharmacy

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  • Parinaz K. Ghaswalla

  • Daniel Tassone

  • Patricia W. Slattum

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