Chimeric antigen receptors redirect T cells to surface antigens. Discovery and validation of appropriate target antigens expand the possible indications for chimeric-antigen receptor (CAR)-T cells. B-cell maturation antigen (BCMA) is expressed only on mature B cells and plasma cells and promotes their survival. BCMA is a promising target for CAR-T cells in multiple myeloma. ©2013 AACR.
CITATION STYLE
Maus, M. V., & June, C. H. (2013, April 15). Zoom zoom: Racing CARs for multiple myeloma. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.CCR-13-0168
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