A two-photon photosensitizer with four triethoxysilyl groups is synthesized through the click reaction. This photosensitizer allows the design of bridged silsesquioxane (BS) nanoparticles through a sol-gel process; moreover, gold core BS shells or BS nanoparticles decorated with gold nanospheres are synthesized. An enhancement of the two-photon properties is noted with gold and the nanoparticles are efficient for two-photon imaging and two-photon photodynamic therapy of cancer cells.
CITATION STYLE
Croissant, J., Maynadier, M., Mongin, O., Hugues, V., Blanchard-Desce, M., Chaix, A., … Durand, J. O. (2015). Enhanced two-photon fluorescence imaging and therapy of cancer cells via Gold@Bridged silsesquioxane nanoparticles. Small, 11(3), 295–299. https://doi.org/10.1002/smll.201401759
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