Microfluidics in Protein Chromatography

Abstract

The development of microfluidics and its utilization in a myriad of applications has grown exponentially over the past 15 years. One area that has benefited from the great strides in fabrication of microelectromechanical systems (MEMS) is separations chemistry. Most studies have focused on small molecule and DNA separations; few on protein chromatographic techniques on microchips. This review details recent developments in protein separations on microfluidic platforms and how MEMS have the potential for revolutionizing protein chromatography.