One-pot synthesis of 2-aminothiazoles in PEG-400

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Abstract

A facile one-pot synthesis of 2-aminothiazoles has been carried in PEG-400 as a greener medium at room temperature. This method avoids the use of lachrymatric α-bromoketones as well as the volatile, toxic organic solvents. © 2009 Ramrao A. Mane.

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Jawale, D. V., Lingampalle, D. L., Pratap, U. R., & Mane, R. A. (2010). One-pot synthesis of 2-aminothiazoles in PEG-400. Chinese Chemical Letters, 21(4), 412–416. https://doi.org/10.1016/j.cclet.2009.11.035

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