Aim: To evaluate the efficacy of a new ablation procedure for the stepwise hook extension technique using a SuperSlim needle for radiofrequency ablation (RFA) treatment of hepatocellular carcinoma (HCC), a randomized controlled trial was performed. Methods: Thirty patients with HCC measuring 20mm or less were randomly treated with a conventional four stepwise expansion technique (group 1) and the new stepwise expansion technique (group 2; the electrode was closed in the shaft after the same three steps of the conventional procedure and then fully extended). All patients underwent the RFA procedure using a 10-hook expandable electrode of 17-G diameter (LeVeen SuperSlim 30mm). We compared the ablation time, required energy and ablated lesions in the two groups. Results: The long and short diameters of RFA-induced necrosis were significantly larger in group 2 (37 and 28mm) than group 1 (30 and 26mm, P=0.001 and =0.045, respectively). Irregular and small needle expansion resulting in the parachute-like or irregularly shaped ablated zone was observed in more cases in group 1 than in group 2. The new technique made all tines expand uniformly and largely, which produced a near-oval ablated zone of which the long axis is perpendicular to the needle shaft. Conclusion: The two kinds of stepwise procedures allow the selection of a more suitable procedure according to the tumor size and shape in each RFA. © 2013 The Japan Society of Hepatology.
CITATION STYLE
Hirakawa, M., Ikeda, K., Kobayashi, M., Kawamura, Y., Hosaka, T., Sezaki, H., … Kumada, H. (2013). Randomized controlled trial of a new procedure of radiofrequency ablation using an expandable needle for hepatocellular carcinoma. Hepatology Research, 43(8), 846–852. https://doi.org/10.1111/hepr.12033
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