Wettable silicone hydrogel contact lenses

  • Lay Y
  • Friends G
  • Valint Jr. P
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Abstract

Improved silicone-contg. hydrogel contact lenses with enhanced wettability comprise a silicone-contg. monomer, hydrophilic monomers, and a relatively non-polar ring-contg. monomer able to be converted to a highly polar amino acid upon hydration. A contact lens was prepd. from IDS3H (a urethane prepolymer), diethylene glycol, polysiloxanediol, and 2-hydroxyethyl methylacrylate 35; methacryloxypropyl tris(trimethylsiloxy)silane 35, N,N-dimethylacrylamide 30; hexanol 40; , benzoin Et ether 0.2; and 2-vinyl-4,4'-dimethyl-2-oxazolin-5-one 5 parts. The water content of the lens was 39%, the O permeability was 70Dk, and tensile modulus was 130 g/mm2. [on SciFinder (R)]

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Lay, Y. C., Friends, G. D., & Valint  Jr., P. L. (1993). Wettable silicone hydrogel contact lenses. PCT Int. Appl. Wo: (Bausch and Lomb Inc., USA).

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