Toward the ultimate metal microelectrode

Abstract

The performance of metal microelectrodes for stimulating and recording neuronal action potentials depends on precise control of their geometrical, electrical and mechanical properties. We describe a combination of materials whose properties approach fundamental physical limitations on achievable performance and reproducible fabrication techniques that provide probes with very small dimensions. Pure iridium wire is electrolytically sharpened, vapor-coated with Parylene-C insulation and the tip exposed using an automatically steerable UV laser. Electrochemical activation of the iridium increases the capacitance of the metal-electrolyte interface so that the overall impedance in the relevant frequency band (100-10 000 Hz) is dominated by the access resistance of the surrounding tissues. © 1995.