Zebrafish as an immunological model system

Abstract

Two decades of research have established the zebrafish (Danio rerio) as a significant model system for studying vertebrate development and gene structure-function relationships. Recent advances in mutation screening, the creation of genomic resources, including the Zebrafish Genome Project and the development of efficient transgenesis procedures, make this model increasingly attractive for immunological study. © 2002 Éditions scientifiques et médicales Elsevier SAS. All rights reserved.