Structural Bioinformatics

In this group: 90 papers · 28 members

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Biological Sciences

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About this group

We do research in the broad field of computational biology, focusing on systems biology and structural biology.

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New updates

Sneha Menon is now following this group

20th May

Andrew Perry is now following this group

15th May

Hira Mirza is now following this group

1st May

Jose C. Jimenez-Lopez has joined this group

18th February

Jose C. Jimenez-Lopez is now following this group

18th February

Seong Kyu Han added documents to this group

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

Evolutionarily Conserved Linkage between Enzyme Fold, Flexibility, and Catalysis

16th February

Jae-Seong Yang added documents to this group

news and views Finding the missing links in EGFR

Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution

16th February

Seong Kyu Han added documents to this group

Transient non-native hydrogen bonds promote activation of a signaling protein.

Dynamic allostery: linkers are not merely flexible.

The dynamic energy landscape of dihydrofolate reductase catalysis.

Atomistic kinetic model for population shift and allostery in biomolecules.

Atomic-level characterization of the structural dynamics of proteins

And 4 more

14th February

Jae-Seong Yang added documents to this group

CoESPRIT: A Library-Based Construct Screening Method for Identification and Expression of Soluble Protein Complexes

Directed evolution of sulfotransferases and paraoxonases by ancestral libraries.

Translation-independent localization of mRNA in E. coli.

Genetic Interaction Maps in Escherichia coli Reveal Functional Crosstalk among Cell Envelope Biogenesis Pathways

8th February

shruti khare is now following this group

6th February

Jae-Seong Yang added a document to this group

PepX: a structural database of non-redundant protein–peptide complexes

6th February

Jae-Seong Yang added a document to this group

ConTra v2: a tool to identify transcription factor binding sites across species, update 2011

5th February

Jae-Seong Yang added a document to this group

MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets.

4th February

Jae-Seong Yang added documents to this group

A physical model for PDZ-domain/peptide interactions

The multiple-specificity landscape of modular peptide recognition domains

Inferring PDZ Domain Multi-Mutant Binding Preferences from Single-Mutant Data

Coevolution of PDZ domain-ligand interactions analyzed by high-throughput phage display and deep sequencing.

Genome-Wide Analysis of PDZ Domain Binding Reveals Inherent Functional Overlap within the PDZ Interaction Network

And 1 more

2nd February

Jae-Seong Yang added documents to this group

Orientational Preferences of Neighboring Helices Can Drive ER Insertion of a Marginally Hydrophobic Transmembrane Helix.

Introduction to theme "membrane protein folding and insertion".

Control of Membrane Protein Topology by a Single C-Terminal Residue.

Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum.

SignalP 4.0: discriminating signal peptides from transmembrane regions

1st February

Jae-Seong Yang added documents to this group

Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase.

Systematic exploration of synergistic drug pairs

Combinations of protein-chemical complex structures reveal new targets for established drugs.

A Systematic Study of the Energetics Involved in Structural Changes upon Association and Connectivity in Protein Interaction Networks.

Slow protein evolutionary rates are dictated by surface-core association.

15th January

Matthieu Chavent is now following this group

4th January

Benoit Felix is now following this group

14th December, 2011

matt cc is now following this group

6th December, 2011

Jae-Seong Yang added a document to this group

Computational design of membrane proteins.

31st October, 2011

Owned by Jae-Seong Yang

Ph.D. Student

Biological Sciences

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Structural Bioinformatics

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