Age-related changes of the anterior chamber width

Abstract

The prevalence of primary angle closure glaucoma (PACG) and of narrow angle width both increase with age. Both also show cross-racial differences. However, little is known about how angle width vanes with age or about the prevalence of narrow angle width in Japanese. In this study, we conducted gonioscopic and biometnc examinations on 585 adult Japanese participants in a glaucoma screening. Prevalence of narrow angle width increased with age. The overall prevalence of grade 1 or narrower angle width and of PACG was 2.6% and 0.3%. respectively, neither of which was significantly different from rates reported among whites. An angle width asymmetry between a subject’s eyes that increased with age appeared to be related to asymmetry of lens thickness, anterior chamber depth, and lens position. PACG is associated with certain biometnc ocular features, each of which significantly correlated with angle width. However, the coefficient of determination calculated by multiple regression analysis was 0.41. suggesting that factors other than those studied are involved in determining the angle width. Key Words: Epidemiology-Population survey-Primary angle closure glaucoma-Biometry-Gonios-copy. © 1992 Raven Press, Ltd.