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A chiral pool based synthesis of platensimycin

Angewandte Chemie - International Edition (2008) 47(5) 944-946
DOI: 10.1002/anie.200705080
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Abstract

(Chemical Equation Presented) Extensive pharming: An expedient entry into the tetracycle 2, a late-stage synthetic intermediate en route to the broad-spectrum antibiotic (-)-platensimycin (1) has been accomplished. The strategy involves a series of cyclizations starting from the inexpensive chiral pool starting material (R)-(-)-carvone. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

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Nicolaou, K. C., Pappo, D., Tsang, K. Y., Gibe, R., & Chen, D. Y. K. (2008). A chiral pool based synthesis of platensimycin. Angewandte Chemie - International Edition, 47(5), 944–946. https://doi.org/10.1002/anie.200705080

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