Copper(I)-catalyzed Caryl-Calkynyl bond formation of aryl iodides with terminal alkynes

Abstract

A wide range of internal alkynes are synthesized from the corresponding aryl iodides and terminal alkynes by Sonogashira-type cross-coupling reactions through Caryl-Calkynyl bond formation in the presence of a catalytic amount of readily available DBU-CuBr complex under mild reaction conditions. © Georg Thieme Verlag Stuttgart.