FPGA-accelerated simulation engine for non-viral gene delivery

Abstract

Computational methods have become an important part of gene delivery research, as they allow researchers to experiment with different models of cellular processes. Models of the gene delivery process based on telecommunication theory make this experimentation especially efficient. Therefore, this paper presents a specialised FPGA-accelerated heterogeneous architecture for simulating the gene delivery process using queuing theory. We also present an implementation of a programmable M/M/∞ queue simulator, and compare its performance to that of an equivalent software simulator. We finally discuss limitations of our system and outline future work aimed at further performance improvement.