Abstract
Knowledge-based systems can model a system, assess its performance, detect abnormalities in its operation, and make suggestions for its safe, stable, and optimal operation by capturing quantitative and heuristic information about a system and using rule-based reasoning to make inferences. A knowledge-based system can interface algorithms and quantitative information with heuristics and rules to yield a powerful environment that can accommodate nonlinearities, uncertainties in information, and rapid shifts in process operation. This chapter introduces knowledge-based and agent-based systems. The latter relies on distributed artificial intelligence and is well-suited for systems with distributed or discrete elements. Three applications are presented to illustrate the capabilities of knowledge-based and agent-based systems: supervision of penicillin fermentation systems, development of a distributed process supervision and fault diagnosis system, and modeling of a mammalian cell bioreactor.
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CITATION STYLE
Cinar, A., & Bayrak, E. S. (2017). Real-Time Knowledge-Based Systems. In Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls (pp. 759–784). Elsevier Inc. https://doi.org/10.1016/B978-0-444-63663-8.00026-4
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