Journal Article

The structure of the homeodomain and its functional implications

Trends in Genetics (1990) 6(C) 323-329
DOI: 10.1016/0168-9525(90)90253-3
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Abstract

The three-dimensional structure of the homeodomain, as determined by nuclear magnetic resonance spectroscopy, reveals the presence of a helix-turn-helix motif, similar to the one found in prokaryotic gene regulatory proteins. Isolated homeodomains bind with high affinity to specific DNA sequences. Thus, the structure-function relationship is highly conserved in evolution. © 1990.

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APA

Gehring, W. J., Müller, M., Affolter, M., Percival-Smith, A., Billeter, M., Qian, Y. Q., … Wüthrich, K. (1990). The structure of the homeodomain and its functional implications. Trends in Genetics, 6(C), 323–329. https://doi.org/10.1016/0168-9525(90)90253-3

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