Synthesis and 1,3-dipolar cycloadditions of a new enantiopure cyclic nitrone

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Abstract

A new enantiopure cyclic nitrone has been efficiently synthesized from a D-glyceraldehyde derivative. Its 1,3-dipolar cycloaddition to different classes of dipolarophiles show complete antifacial selectivity, furnishing highly functionalized enantiopure bicyclic isoxazolidines. © 2002 Elsevier Science Ltd. All rights reserved.

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Alibés, R., Blanco, P., De March, P., Figueredo, M., Font, J., Álvarez-Larena, Á., & Piniella, J. F. (2003). Synthesis and 1,3-dipolar cycloadditions of a new enantiopure cyclic nitrone. Tetrahedron Letters, 44(3), 523–525. https://doi.org/10.1016/S0040-4039(02)02587-X

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