Sentinel node detection by Crystal Cam in breast cancer: Accuracy and contribution to ambulatory surgery

Abstract

Purpose of investigation: Sentinel lymph node biopsy (SLNB) has become the standard practice for N0 breast cancer. The purpose of this study was to validate the SLN detection accuracy of a handheld gamma camera (Crystal Cam). Materials and Methods: One hundred seven patients underwent double lymphatic mapping combining lymphoscintigraphy and Crystal Cam scintigraphy. The number of SLN excised was compared to the number of SLN detected with both techniques. Pearson's correlation coefficient was calculated. Results: The Crystal Cam detected the same number of SLN than the number excised for 71 patients (66.35%) vs. 57 patients (53.27%) with lymphoscintigraphy. Pearson's coefficient correlation was ? = 0,58 for Crystal Cam, vs. ? = 0,35 for lymphoscintigraphy. Discussion: SLN detection by Crystal Cam appeared to be as effective and accurate as lymphoscintigraphy. The main advantage of Crystal Cam is improving time constraints due to lymphoscintigraphy, thus facilitating ambulatory surgery. Conclusion: Axillary lymphatic mapping by Crystal Cam is a simple, accurate, and reproducible technique for SLNB, allowing more patients to access ambulatory surgery.