Tumour metabolites hinder DNA repair

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Abstract

Altered metabolism and genome instability are hallmarks of cancer. A mechanism now explains how three small molecules that accumulate in tumours connect abnormal metabolism to genomic problems by hindering DNA repair.

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Chen, L. L., & Xiong, Y. (2020, June 25). Tumour metabolites hinder DNA repair. Nature. Nature Research. https://doi.org/10.1038/d41586-020-01569-1

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