Cognitive impairment in schizophrenia

Abstract

Conventionally, a major deficiency in cognitive functions was believed to occur only in elderly individuals with chronic schizophrenia. Over the past three decades, the results of several studies have provided evidence to the contrary. The current view is that marked cognitive impairment is not only common but may even pre-date the disorder. Research in the area of neurocognition in schizophrenia has resulted in unlocking various secrets of schizophrenia, such as disclosing the biological underpinnings and explaining the underlying psychopathology and matters related to the course, outcome and treatment approaches. This chapter sets out the evidence for cognitive impairments in schizophrenia and seeks to justify their importance, particularly concerning pharmacological and cognitive remediation. Tracing the evaluation of neurocognitive science may provide new insights into the pathophysiology and treatment of psychiatric disorders.