Recommendations of the Brazilian Society of Rheumatology for the diagnosis and treatment of chikungunya fever. Part 2 – Treatment

  • Marques C
  • Duarte A
  • Ranzolin A
  • et al.
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© 2017 Chikungunya fever has become a relevant public health problem in countries where epidemics occur. Until 2013, only imported cases occurred in the Americas, but in October of that year, the first cases were reported in Saint Marin island in the Caribbean. The first autochthonous cases were confirmed in Brazil in September 2014; until epidemiological week 37 of 2016, 236,287 probable cases of infection with chikungunya virus (CHIKV) had been registered, 116,523 of which had serological confirmation. Environmental changes caused by humans, disorderly urban growth and an ever‐increasing number of international travelers were described as the factors responsible for the emergence of large‐scale epidemics. Clinically characterized by fever and joint pain in the acute stage, approximately half of patients progress to the chronic stage (beyond 3 months), which is accompanied by persistent and disabling pain. The aim of the present study was to formulate recommendations for the diagnosis and treatment of chikungunya fever in Brazil. A literature review was performed in the Medline, SciELO and PubMed databases to ground the decisions for recommendations. The degree of concordance among experts was established through the Delphi method, involving 2 in‐person meetings and several online voting rounds. In total, 25 recommendations were formulated and divided into 3 thematic groups: (1) clinical, laboratory and imaging diagnosis; (2) special situations; and (3) treatment. The first 2 themes are presented in part 1, and treatment is presented in part 2.




Marques, C. D. L., Duarte, A. L. B. P., Ranzolin, A., Dantas, A. T., Cavalcanti, N. G., Gonçalves, R. S. G., … Christopoulos, G. (2017). Recommendations of the Brazilian Society of Rheumatology for the diagnosis and treatment of chikungunya fever. Part 2 – Treatment. Revista Brasileira de Reumatologia (English Edition), 57, 438–451.

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