Can sars-cov-2 infection lead to neurodegeneration and parkinson’s disease?

25Citations
Citations of this article
69Readers
Mendeley users who have this article in their library.

Abstract

The SARS-CoV-2 pandemic has affected the daily life of the worldwide population since 2020. Links between the newly discovered viral infection and the pathogenesis of neurodegenerative diseases have been investigated in different studies. This review aims to summarize the literature concerning COVID-19 and Parkinson’s disease (PD) to give an overview on the interface between viral infection and neurodegeneration with regard to this current topic. We will highlight SARS-CoV-2 neurotropism, neuropathology and the suspected pathophysiological links between the infection and neurodegeneration as well as the psychosocial impact of the pandemic on patients with PD. Some evidence discussed in this review suggests that the SARS-CoV-2 pandemic might be followed by a higher incidence of neurodegenerative diseases in the future. However, the data generated so far are not sufficient to confirm that COVID-19 can trigger or accelerate neurodegenerative diseases.

Cite

CITATION STYLE

APA

Krey, L., Huber, M. K., Höglinger, G. U., & Wegner, F. (2021, December 1). Can sars-cov-2 infection lead to neurodegeneration and parkinson’s disease? Brain Sciences. MDPI. https://doi.org/10.3390/brainsci11121654

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free