14-3-3σ is a protein expressed in many epithelial tissues associated with essential cell functions, including cell-cycle control, apoptosis, and cytoskeletal integrity. There is a paucity of knowledge of the tumorigenesis of canine renal cell carcinomas (RCCs), and the histological origin of this tumor has not been established. This study analyzed the expression of 14-3-3σ, Ki-67, cytokeratins, and vimentin in 40 canine RCCs. Aberrant expression of 14-3-3σ was demonstrated in 15 (38%) cases and was associated with a significantly shorter survival time (P
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Suárez-Bonnet, A., Lara-García, A., Stoll, A. L., Carvalho, S., & Priestnall, S. L. (2018). 14-3-3σ Protein Expression in Canine Renal Cell Carcinomas. Veterinary Pathology, 55(2), 233–240. https://doi.org/10.1177/0300985817738097