Predicting and preventing measles epidemics in New Zealand: Application of a mathematical model

Abstract

A mathematical model of the dynamics of measles in New Zealand was developed in 1996. The model successfully predicted an epidemic in 1997 and was instrumental in the decision to carry out an intensive MMR (measles-mumps-rubella) immunization campaign in that year. While the epidemic began some months earlier than anticipated, it was rapidly brought under control, and its impact on the population was much reduced. In order to prevent the occurrence of further epidemics in New Zealand, an extended version of the model has since been developed and applied to the critical question of the optimal timing of MMR immunization.