Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

Abstract

Herein, we reported nitroxide radical-modified CuS nanoparticles (CuS-NO NPs), and they exhibited a typical absorption peak at 1182 nm. Due to such a long wavelength absorbance, CuS-NO NPs exhibited excellent therapeutic outcome and low damage to normal tissues. Besides, we simultaneously achieved CuS-NO NPs for MRI and CT dual-modal imaging, which successfully provided a new strategy for imaging-guided tumor treatment, thus increasing potential clinical applications for cancer treatment.