Biological therapy after COVID-19 infection: No reactivation of a COVID-19 infection with positive SARS-CoV-2 antibody status under biological therapy

Abstract

A case with rheumatoid arthritis and insufficient compensation under disease-modifying combined long-term therapy with methotrexate and leflunomide is reported. After recovery from a COVID-19 infection, a tumor necrosis factor (TNF) inhibitor therapy was initiated. Until now no reactivation of the COVID-19 infection with positive SARS-CoV‑2 antibody status has occurred.