Effects of a Novel Therapeutic Intervention in Patients with Diabetic Peripheral Neuropathy

Abstract

Objective To determine the effect of a novel therapeutic intervention called intraneural facilitation on balance measures and a neuropathy scale in patients with diabetic peripheral neuropathy. Design Prospective pre- and posttest, single group clinical trial. Setting Outpatient physical therapy clinic. Participants Patients with diabetic peripheral neuropathy (N=13). Intervention Subjects received 10 sessions of intraneural facilitation. Main Outcome Measures The modified Total Neuropathy Scale, the NeuroCom SMART Balance Master system computerized dynamic posturography (CDP) that includes the Sensory Organization Test (SOT) and the limits of stability (LOS), and the Activities-specific Balance and Confidence (ABC) scale. Results Subjects in this study showed significant improvement in the modified Total Neuropathy Scale, SOT, and 1 component in the LOS test (movement velocity). There were no significant differences in the ABC scale or in 4 components of the LOS test, which were reaction time, end point excursion, maximum excursion, and directional control. Conclusions Intraneural facilitation improved objective balance measures and neuropathy symptoms in patients with diabetic peripheral neuropathy. Further study is needed to determine long-term benefits of this intervention.