Changes in the morphology, mechanical strength and biocompatibility of polymer and metal/polymer fabricated hydroxyapatite for orthopaedic implants: a review

Abstract

Hydroxyapatite (HAp) is a well-known bioceramic known for its high biocompatibility and good bioactivity. The structure of HAp mimics the natural bone structure and thus, it is widely used as implants for hard tissues. Despite possessing the above properties, it lacks mechanical strength, is susceptible to the growth of microbes over time and has low degradability. Polymers can be synthetic or natural. They can be a better choice to be used as additives to improve the properties of HAp due to its better mechanical strength and high biodegradability. A combination of metals and polymers together can overcome the drawbacks of HAp to a greater extent. This review article deals with different polymers and metal/polymer fabricated HAp to show the changes in the properties of HAp following the substitution. It also deals with how better they could be used as a hard tissue implant.