Performance of the roche lightcycler real-time PCR assay for diagnosing extrapulmonary tuberculosis

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Abstract

The Roche LightCycler mycobacterium detection molecular assay for Mycobacterium tuberculosis, M. avium, and M. kansasii, was applied to tissue specimens. It performed well on lymph node and cerebrospinal fluid specimens and less well on lung, liver, and bone marrow core biopsy specimens, but used in conjunction with a clinical suspicion of tuberculosis, it could augment patient management. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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Gous, N., Scott, L. E., Wong, E., Omar, T., Venter, W. D. F., & Stevens, W. (2012). Performance of the roche lightcycler real-time PCR assay for diagnosing extrapulmonary tuberculosis. Journal of Clinical Microbiology, 50(6), 2100–2103. https://doi.org/10.1128/JCM.00252-12

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