Plasma concentrations of oestradiol 17β, oestrone, progesterone and testosterone during the ovarian cycle of the owl monkey (Aotus trivirgatus)

Abstract

Oestrone, oestradiol-17β, progesterone and testosterone were measured by radioimmunoassay in daily plasma samples throughout the ovarian cycle in 4 female owl monkeys. Clearly defined peaks of oestradiol-17β occurred at intervals of 15·5 ± 0·56 days and confirmed the length of the cycle reported previously. Progesterone rose on the day of the oestradiol-17β peak to reach a maximum 4-6 days later, thereafter decreasing gradually to low levels before the onset of the next cycle. On the basis of these data the follicular and luteal phases were estimated to be 6 and 10 days respectively. Oestrone and testosterone peaks preceded that of progesterone by 24 h and remained elevated throughout the luteal phase. Plasma concentrations of all steroids were markedly higher than for other primate species. Vaginal cytology was considered unsuitable as an indicator of the stage of the ovarian cycle.