Physostigmine reversal of psilocybin intoxication

Abstract

A case of acute intoxication caused by eating mushrooms containing psilocybin, an anti-serotonergic drug known to cause hallucinations is described. This case of proven psilocybin intoxication is presented as an anticholinergic syndrome. Rapid reversal of all symptoms was obtained by the intravenous administration of physostigmine.