Ginger (Zingiber officinale Roscoe) Bioactive Components: Potential Resources for Kidney Health

Abstract

Ginger (Zingiber officinale Roscoe), being a customary dietary component across various regions globally, possesses numerous biological functionalities, such as antioxidative, anti-inflammatory, immune-regulatory, and anti-apoptotic properties. Ginger plays a crucial role in the management of kidney health due to its bioactive constituents, which are extensively implicated in various processes, including antioxidant activity, anti-inflammatory activity, amelioration of endothelial dysfunction, inhibition of cell apoptosis and necrosis, mitigation of renal fibrosis, and promotion of autophagy. In clinical trials, it was also found that the effect of ginger on blood sugar, blood lipid, and inflammatory factors could improve kidney function. These studies summarize the ginger active ingredients and their potential functions in the protection of kidney health, and provide an overview of the application and targeted delivery of ginger bioactive in functional food. In the future, more health-related information of bioactive compounds in ginger is needed, and their health effects for kidney should be further investigated.