Plasma transfusion to prevent intraventricular haemorrhage in very preterm infants

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: Primary objective: To assess whether plasma transfusion administered within the first 24 hours of life can prevent IVH in preterm infants born at gestation less than or equal to 34 weeks. Secondary objective: To determine whether use of plasma transfusion is associated with adverse effects. Subgroup analyses: We will perform the following subgroup analyses. Known coagulapathy versus unknown coagulation status versus normal coagulation status. Gestational age. Birth weight. Type of plasma administered. Volume of plasma administered. Timing of administration. Known to have no IVH versus unknown status at randomisation.