A REVIEW ON FORMULATION APPROACHES IN IMMEDIATE RELEASE TABLET

Abstract

Sometimes immediate onset of action is required than conventional treatment in many patients. Among all dosage forms tablet is the most popular dosage form existing today because of its convenience of self-administration, compactness and easy manufacturing. to overcome these drawbacks, immediate release dosage form has emerged as alternative oral dosage forms. Immediate drug release dosage forms disintegrate quickly after administration with enhanced rate of dissolution. The basic approach used in development tablets is the use of superdisintegrants like Cross linked Polyvinylpyrrolidone or crospovidone (Polyplasdone), Sodium starch glycolate (Primogel, Explotab), carboxymethylcellulose (Croscarmellose) etc. In this field immediate release liquid dosage forms and parenteral dosage form have also been introduced for treating patients. The development of immediate release therapy also provides an opportunity for a line extension in the marketplace, a wide range of drugs e.g., anticoagulant and other drugs can be considered candidates for this dosage form. The development of immediate release therapy also provides an opportunity for a line extension in the marketplace, a wide range of drugs e.g., anticoagulant and other drugs can be considered candidates for this dosage form.