Technology for the production of disubstituted pyrroles

Abstract

In this work, we studied the catalytic synthesis of pyrrole and their derivatives from ketoximes and acetylene in the liquid phase under normal conditions in the presence of homogeneous catalysts. Mathematical modeling of the experiment was carried out using the Box-Wilson method and the optimal conditions for the synthesis of a number of pyrroles were found. The catalytic synthesis of pyrrole under vapor phase conditions in the presence of heterogeneous catalysts has been studied. Low-temperature polyfunctional catalysts have been developed that provide the highest yield of pyrroles.