Ionic liquids as the catalysts for asymmetric reactions

Abstract

A new 7 functionalized chiral ionic liquids (CILs) based on pyrrolidine have been synthesized from (S)-proline as a main substrat. The obtained compounds have 1-[(S)-(pyrrolidin-2-yl)methyl]-3-alkylimidazolium cation and bis(trifluoromethylsulfonyl)imide and hexafluorophosphate anions. The structures of the obtained catalysts were determined by spectroscopic analysis 1HNMR, 13CNMRand 19F NMR. This chiral ionic liquids have been applied as efficient catalysts for Michael addition of cyclohexanone to nitroalkenes.