Dissecting the role of the N-terminal region of the Escherichia coli global transcription factor FNR

Abstract

The role of the N-terminal region of the transcription factor FNR, which immediately precedes the first ligand (Cys20) of the [4Fe-4S] cluster, was investigated. We found that truncation mutants that removed residues 2 to 16 and 2 to 17 had wild-type levels of FNR protein but surprisingly altered O 2 regulation. Copyright © 2008, American Society for Microbiology. All Rights Reserved.