Research Progress of 3D Printing Microfluidic Chip

Abstract

Because of the advantages of microfluidic technology, such as high detection speed, high accuracy and low reagent loss, it has obvious advantages over the traditional detection technology. So recently, microfluidic technology has been widely used in life science and medical diagnosis. However, the microfluidic chip processing technology is mostly developed from semiconductor processing technology, which has the characteristics of high cost and high technical requirements, which are also important factors limiting the development of microfluidic technology. In recent years, 3D printing technology has become more and more mature, so using 3D printing technology to make microfluidic chips has attracted the attention of many researchers. Compared with the traditional microfluidic chip processing technology, 3D printing microfluidic chip technology has been widely concerned because of its advantages of fast design and processing speed, wide material adaptability and low cost. At present, the processing methods of microfluidic chip mainly include micro stereolithography, deposition molding, ink-jet printing and so on. In this paper, the main research progress of 3D printing microfluidic chips at home and abroad and the future development direction are reviewed. At last, the applications of microfluidic chip processing technology in analytical chemistry, life science, medical diagnosis and other fields are prospected.