Catalytic Activation of Unstrained, Nonactivated Ketones Mediated by Platinum(II): Multiple C-C Bond Cleavage and CO Extrusion

Abstract

The complexes [Pt(tolpy)Cl(L)] (tolpy = 2-(4-tolyl)pyridyl; L = dmso, dms, py, PPh3, CO) are precursors for the catalytic cleavage of C-C bonds and extrusion of CO from a series of unactivated ketones such as cyclohexanone; deuterium labeling experiments demonstrate the involvement of a transfer hydrogen step in the mechanism.