RP‐HPLC Determination of Raloxifene in Pharmaceuticl Tablets

  • Reddy P
  • Rani B
  • Babu G
  • et al.
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Abstract

A reverse phase HPLC method is developed for the determination of Raloxifene in pharmaceutical dosage forms. Chromatography was carried out on an inertsil C18 column using a mixture of acetonitrile and phosphate buffer (30:70 v/v) as the mobile phase at a flow rate of 1 mL/min. Detection was carried out at 290 nm .The retention time of the drug was 10.609 min. The method produced linear responses in the concentration range of 0.5‐200 µg/mL of Raloxifene. The method was found to be applicable for determination of the drug in tablets.

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Reddy, P. V., Rani, B. S., Babu, G. S., & Rao, J. V. L. N. S. (2006). RP‐HPLC Determination of Raloxifene in Pharmaceuticl Tablets. Journal of Chemistry, 3(1), 60–64. https://doi.org/10.1155/2006/713569

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